What is Botox for Trigeminal Neuralgia?
Trigeminal neuralgia is a condition that causes sudden, severe facial pain along the trigeminal nerve, often triggered by simple activities like chewing, talking, or touching the face. Botox is an off-label treatment (not officially FDA-approved for this use but supported by research and clinical practice) that can help by blocking pain signals and relaxing the muscles around the affected nerve. For some patients, this reduces the frequency and intensity of painful attacks.
How do you prepare for Botox for Trigeminal Neuralgia?
- Tell your doctor about all medicines, especially blood thinners.
- Share your pain history — how often attacks happen and what triggers them.
- Come with clean skin on your face (no heavy creams or makeup).
- Most people do not need special fasting or restrictions but follow any instructions your doctor gives.
Why is Botox for Trigeminal Neuralgia performed?
- To reduce severe facial pain attacks when medications (like carbamazepine or gabapentin) do not work well or cause too many side effects.
- To improve quality of life, since trigeminal neuralgia pain can be disabling.
- To provide an alternative option for patients who are not candidates for or wish to avoid surgery.
What can you expect during Botox for Trigeminal Neuralgia?
- The procedure is done in a clinic and takes about 15–30 minutes.
- A very fine needle is used to inject small amounts of Botox into the skin and muscles of the face near where the trigeminal nerve runs.
- The exact injection sites depend on your pain pattern.
- The injections may feel like quick pinches or stings.
- You can return home the same day and resume normal activities.
What is the follow-up like for Botox for Trigeminal Neuralgia?
- Pain relief usually begins within 3 days and peaks around 3 weeks.
- Effects last about 3 months, after which repeat injections may be needed.
- Your doctor will track how much your pain improves and may adjust injection sites or doses.
- Botox is often combined with other treatments (like medications or nerve procedures) for best results.
What are the potential risks for Botox for Trigeminal Neuralgia?
Most side effects are mild and temporary:
- Pain, redness, or swelling at the injection site.
- Temporary facial weakness or drooping, depending on injection sites.
Rare but more serious risks include:
- Allergic reaction.
- Spread of toxin effect leading to swallowing or speaking difficulty (very uncommon when done properly).
Are there related tests to Botox for Trigeminal Neuralgia?
- A neurological exam and your pain history are most important.
- MRI scans are often done before treatment to rule out other causes of nerve pain (like tumors or multiple sclerosis).
- Botox itself doesn’t require special tests, but your doctor may monitor progress with a pain diary.

Providing specialized neurological and pain management care with a patient-centered approach. Dr. Sader combines clinical expertise with compassionate care to help patients achieve optimal health outcomes.