What is an SPG Block?
An SPG block is a procedure that numbs the sphenopalatine ganglion (SPG) — a group of nerves located behind the nose and deep in the face. These nerves are involved in certain types of head and face pain. An SPG block can help treat migraines, cluster headaches, trigeminal neuralgia, and other severe facial or head pain by calming overactive pain signals.
How do you prepare for an SPG Block?
- Tell your doctor about all medicines you take, especially blood thinners or nasal medications.
- Discuss allergies to numbing medicines (local anesthetics).
- You can eat and drink normally before the procedure.
- Avoid heavy nasal sprays or decongestants on the day of the procedure unless instructed.
- Tell your doctor if you had any sinus or nasal/ENT surgeries.
Why is an SPG Block performed?
- To reduce severe headache or facial pain, especially migraines or cluster headaches that don’t respond well to medication.
- To relieve pain quickly during an acute headache attack.
- To help with other pain conditions such as atypical facial pain.
What can you expect during an SPG Block?
- The procedure is done in a doctor’s office and takes 10–20 minutes.
- You’ll lie on your back with your head slightly tilted back.
- The doctor inserts a thin, soft applicator or catheter into one or both nostrils to reach the SPG area.
- Numbing medicine (local anesthetic) is applied or injected to the nerves.
- You may feel mild pressure, coolness, or a brief bitter taste in the throat.
- After a few minutes, your nose, throat, may feel numb.
- You can go home the same day.
What is the follow-up like for an SPG Block?
- Pain relief can begin within minutes to hours after the block.
- Results can last from days to weeks — sometimes longer with repeated treatments.
- Mild numbness or throat fullness usually wears off within a few hours. Avoid eating during this time.
- Your doctor may combine SPG blocks with other headache or pain treatments.
What are the potential risks for an SPG Block?
Most side effects are mild and short-lived, such as:
- Temporary numbness in the throat, nose, or palate.
- Watery eyes or nasal drainage.
- Flushing in the face (We use this as a tool to ensure the block worked).
- Mild dizziness or bitter taste in the mouth.
Less common risks include:
- Nosebleed.
- Soreness or irritation in the nose.
- Infection (rare).
- Allergic reaction to the numbing medicine (very rare).
Are there related tests to an SPG Block?
- Usually, no special tests are required before an SPG block.
- Imaging (MRI or CT scans) may be done if there’s uncertainty about the cause of headaches or facial pain.
- A neurological exam may help your doctor decide if an SPG block is appropriate.

Providing specialized neurological and pain management care with a patient-centered approach. Dr. Sader combines clinical expertise with compassionate care to help patients achieve optimal health outcomes.